Static headspace analysis is often considered to be useful only when the analytes of interest are present in high concentrations. Although techniques like solid phase microextraction (SPME) and dynamic headspace (DHS) have better extraction effi ciencies, due to advances in mass spectrometry design, VOCs can now be detected in the parts per billion range using static headspace. Static headspace is routinely used for blood alcohol determination and for the analysis of residual solvents in pharmaceuticals. Method development is fast and simple, usually with little to no sample preparation.

Laboratory samples are typically extracted prior to analysis by sensitive GC-MS or LC-MS/MS methods to separate the analytes of interest from the bulk of matrix components ...

In this study, Thin Film Solid Phase Micro-Extraction (TF-SPME) devices with carboxen/polydimethylsiloxane (CAR/PDMS), divinylbenzene/polydimethylsiloxane (DVB/PDMS), and hydrophilic lipophilic balanced/polydimethylsiloxane (HLB/PDMS) coatings are investigated for their usefulness for beverage analysis in combination with Stir Bar Sorptive Extraction (SBSE) using the GERSTEL Twister®. A variety of beverages are analyzed including almond milk, black tea, strawberry banana juice, amber lager, and pumpkin ale. The GERSTEL MPS is used in combination with a CIS 4 inlet and thermal desorber for automated thermal desorption of the TF-SPME devices.

In this study, Thin Film Solid Phase Microextraction (TF-SPME) with a divinylbenzene/polydimethylsiloxane coating (DVB/PDMS) was used to extract off-odor compounds from paper product samples. The use of gas chromatography-mass spectrometry directly coupled with olfactory detection (GC-MS/O) enabled simultaneous detection of off-odor regions of the chromatogram and mass spectral identification of off-odor compounds. Identification of off-odor compounds in consumer goods is crucial for the manufacturer in order to identify the cause, take corrective action, and thereby maintain brand acceptance and success.

MCPD and Glycidol and especially their fatty acid esters are process contaminants that are formed, for example, when edible oils and fats are refi ned.

Metabolomics aims to identify the changes in endogenous metabolites of biological systems in response to intrinsic and extrinsic factors in clinical, food and nutrition ...

Synthetic cathinones (also known as Bath Salts) are a group of drug compounds designated as Novel Psychoactive Substances (NPS). They are unregulated, mind-altering substances with no actual approved medicinal use. Since they are cheap substitutes for other stimulants like methamphetamine and cocaine, users will unfortunately turn to these addictive and in some cases even more dangerous alternatives to achieve the desired euphoric effects.

There is a critical need for forensic, health care, and law enforcement scientists to be able to quickly assess and monitor which synthetic cathinone is involved, in order to effectively respond to cases involving these compounds.

In this document we describe a method developed to quantify persistent organic pollutants (POPs) in-cluding polycyclic aromatic hydrocarbons (PAHs) and organochlorine pesticides (OCPs) in dietary sup-plements using stir bar sorptive extraction (SBSE)-GCMS/MS-isotope dilution mass spectrometry (IDMS). This method enables accurate, precise, and sensitive quantification of POPs in plant-extract based dietary supplement products commercially available in the United States. When compared with calibration curves, IDMS provided more accurate and precise measurements. The mean error of measurements using this method was 7.24% with a mean RSD of 8.26%.

Stir Bar Sorptive Extraction (SBSE) coupled with gas chromatography-mass spectrometry and olfactory detection (GC-MS/O) allows for separation and identifi cation of aroma compounds in complex sample matrices with minimal sample preparation time. Aroma Dilution Analysis (ADA) is a solvent-free approach of Aroma Extract Dilution Analysis (AEDA) which employs a GC inlet system to split the carrier gas fl ow and thereby the injected sample to a desired ratio. The approach of ADA has been applied to direct immersion SBSE of bourbon samples for determination of fl avor dilution (FD) factors and identifi cation of key aroma-active compounds.

Plastics, micro- and nanoplastics pollution in oceans, lakes and other water sources is a well-documented issue. Uptake of these particles by shellfish and fish is one avenue for the pollutants to enter the food chain and cause possible adverse effects. Microand nanoplastics are commonly used in commercially available products as abrasives. They end up in the environment through drain disposal since they are not always efficiently removed in the waste water treatment process.

Raman and infrared spectroscopy are often used for identification, but dyes used in the plastic material can sometimes hamper identification using these techniques.