Modern capillary GC injection generally uses the universal dual mode split/splitless injection port or inlet in which the pneumatic mode is selected at the outset. The inlet is maintained at a sufficiently high set temperature to allow instant vaporization of the sample after deposition in the inlet liner (usually 4mm i.d.) Of course this explosive vaporization is associated with the well documented undesirable phenomenon of needle discrimination. If analytes are in aqueous solution another effect is induced by the very high saturated vapor volume of water compared to other solvents. A 1 μL injection of water in hot splitless mode will give a vapor volume greater than the retaining capacity of the liner and can inhibit the subsequent vaporization of analytes.

This study shows the use of the GERSTEL MPS 2/TDU/CIS with pyrolysis module for generating simulated thermal gravimetric-mass spectrometry data (TGA-MS) of ...

Acrylamide is thought to be produced during the roasting process associated with coffee production. Acrylamide has been labeled as a probable human carcinogen. Due to the use of roasted coffee beans in making coffee and the high consumption of coffee worldwide, brewed coffee could be a source of daily exposure to acrylamide. Acrylamide determination has been shown to be challenging due to presence of coextractives in the final extract. Manual solid phase extraction followed by LC-MS/MS analysis has been reported as a successful method for the determination of acrylamide from brewed coffee samples.

16 phenolic compounds along with typical drinking water off-flavor compounds like geosmin, 2-methylisoborneol (MIB), and 2,4,6-trichloroanisole (TCA) were determined ...

This application note describes a fully automated analysis method for selected equine doping compounds in equine urine. A GERSTEL MultiPurpose Sampler (MPS) with Disposable Pipette Extraction (DPX) option is employed for extraction and cleanup. After gas chromatographic separation the analytes are detected by a triple-quadrupole mass spectrometer (QqQ-MS).

A procedure is presented for quantification of Ethyl Carbamate at low μg/L levels in distilled spirits. A 100 μL large volume injection was used followed by orthogonal 2-dimensional GC-MS with heartcutting. The direct large volume injection ensured sufficient availability of analyte without an initial sample preparation step, and the 2D step allowed clean elution of ethyl carbamate and it’s labelled internal standard and compensated for the difficult detection of low mass non-specific ions in a complex matrix. The 2D separation was achieved using the new GERSTEL μFlow- Manager based on metal ferrules for simple connection of the orthogonal columns.

Identification of important trace components in complex samples like fragrances, natural products, polymers or food products can be challenging. Achieving the mass on column and resolution necessary to locate peaks and identify trace components using a single column chromatographic separation can be difficult, if not impossible.

Evaporative Concentration of Substances Listed in the European Water Framework Directive (2000/60/EC and 2008/105/EC). A Performance Comparison ...

The ability to perform accurate qualitative and quantitative analysis of perfumes or flavored products is essential to the flavor and fragrance industry. Especially when unknown samples need to be analyzed, traditional methods of GC analysis often lead to only qualitative results and often rely on time consuming and cumbersome sample preparation techniques such as solvent extraction (liquid/liquid, Soxhlet, Likens-Nickerson).

This study shows the analysis of several commercially available coconut water products using a GC/MS system equipped with a versatile autosampler and sample preparation robot capable of performing a wide range of standard sample introduction techniques including thermal desorption. A fast and efficient analysis method based on stir bar sorptive extraction (SBSE) in combination with thermal desorption -GC/MS was developed for the determination of flavor compounds, pesticides, antioxidants, compounds migration from packaging materials, and off-flavors in coconut water.